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Dephos Chewable Tablet

Dephos Chewable Tablet

Description

⚕️ Indications

  • Control of serum phosphorus levels in CKD patients on dialysis .


💊 Dosage & Administration

  • Starting Dose1 tablet (500 mg) three times daily with meals (totaling 1,500 mg/day).

  • AdministrationTablets should be chewed or crushed; do not swallow whole.

  • Dose AdjustmentAdjust by 500 mg per day as needed to achieve target serum phosphorus levels, with regular monitoring.

  • Missed DoseIf a dose is missed, resume with the next meal; do not double the dose.

  • Pediatric UseSafety and efficacy in pediatric patients have not been established .


⚠️ Precautions & Warnings

  • Gastrointestinal DisordersUse with caution in patients with significant gastric or hepatic disorders, recent gastrointestinal surgery, or peritonitis during peritoneal dialysis.

  • Iron Accumulation DisordersMonitor iron levels in patients with conditions like hemochromatosis, as sucroferric oxyhydroxide contains iron .skfbd.com+5Medex+5Medex+5


🔄 Drug Interactions

  • Can Be Taken Concurrently With:

    • Calcitriol, ciprofloxacin, digoxin, enalapril, furosemide, HMG-CoA reductase inhibitors, hydrochlorothiazide, losartan, metoprolol, nifedipine, omeprazole, quinidine, and warfarin.

  • Timing Considerations:

    • Take acetylsalicylic acid, cephalexin, and doxycycline at least 1 hour before Dephos.

    • Take levothyroxine at least 4 hours before Dephos.

  • Other MedicationsFor oral drugs not listed, consider separating administration times to avoid reduced bioavailability .


🚨 Side Effects

  • Common side effects include discolored feces (12%) and diarrhea (6%) in hemodialysis patients .


🤰 Pregnancy & Lactation

  • Pregnancy Category BAnimal studies have not shown harm to the fetus, but there are no adequate studies in pregnant women.

  • LactationMinimal iron absorption suggests low risk of excretion into breast milk .


🧊 Storage

  • Store below 25°C.

  • Keep away from light and moisture.

  • Keep out of reach of children .


 

NoteAlways consult a registered healthcare professional before starting or adjusting any medication.

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