Description
⚕️ Indications
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Control of serum phosphorus levels in CKD patients on dialysis .
💊 Dosage & Administration
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Starting Dose: 1 tablet (500 mg) three times daily with meals (totaling 1,500 mg/day).
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Administration: Tablets should be chewed or crushed; do not swallow whole.
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Dose Adjustment: Adjust by 500 mg per day as needed to achieve target serum phosphorus levels, with regular monitoring.
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Missed Dose: If a dose is missed, resume with the next meal; do not double the dose.
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Pediatric Use: Safety and efficacy in pediatric patients have not been established .
⚠️ Precautions & Warnings
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Gastrointestinal Disorders: Use with caution in patients with significant gastric or hepatic disorders, recent gastrointestinal surgery, or peritonitis during peritoneal dialysis.
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Iron Accumulation Disorders: Monitor iron levels in patients with conditions like hemochromatosis, as sucroferric oxyhydroxide contains iron .skfbd.com+5Medex+5Medex+5
🔄 Drug Interactions
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Can Be Taken Concurrently With:
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Calcitriol, ciprofloxacin, digoxin, enalapril, furosemide, HMG-CoA reductase inhibitors, hydrochlorothiazide, losartan, metoprolol, nifedipine, omeprazole, quinidine, and warfarin.
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Timing Considerations:
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Take acetylsalicylic acid, cephalexin, and doxycycline at least 1 hour before Dephos.
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Take levothyroxine at least 4 hours before Dephos.
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Other Medications: For oral drugs not listed, consider separating administration times to avoid reduced bioavailability .
🚨 Side Effects
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Common side effects include discolored feces (12%) and diarrhea (6%) in hemodialysis patients .
🤰 Pregnancy & Lactation
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Pregnancy Category B: Animal studies have not shown harm to the fetus, but there are no adequate studies in pregnant women.
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Lactation: Minimal iron absorption suggests low risk of excretion into breast milk .
🧊 Storage
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Store below 25°C.
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Keep away from light and moisture.
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Keep out of reach of children .
Note: Always consult a registered healthcare professional before starting or adjusting any medication.


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