Description
Liposem 2 mg Tablet
Generic Name: Saroglitazar Magnesium
Brand Name: Liposem
Strength: 2 mg
Form: Oral Tablet
Pack Size: 3 x 10 Tablets (30 tablets per box)
Manufacturer: Everest Pharmaceuticals Ltd.
Distributed by: NP Molecule
Indications:
Liposem (Saroglitazar Magnesium) is indicated for the management of:
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Dyslipidemia, particularly diabetic dyslipidemia
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Hypertriglyceridemia in type 2 diabetic patients not controlled with statin therapy alone
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Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) (off-label use in some regions)
Pharmacology:
Saroglitazar is a dual PPAR (Peroxisome Proliferator-Activated Receptor) α/γ agonist.
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PPAR-α activation helps reduce triglycerides and LDL cholesterol
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PPAR-γ activation improves insulin sensitivity and glucose metabolism
Together, it addresses both lipid abnormalities and insulin resistance, offering a comprehensive metabolic benefit in patients with type 2 diabetes and associated lipid disorders.
Dosage & Administration:
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Standard dosage: 2 mg once daily, taken orally
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May be taken with or without food
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Dosage adjustments are generally not needed in mild to moderate hepatic/renal impairment
Drug Interactions:
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Minimal CYP450 interaction; low risk of drug-drug interactions
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Can be used safely with statins, metformin, and other antidiabetic agents
Contraindications:
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Hypersensitivity to Saroglitazar or any tablet components
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Severe hepatic impairment
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History of bladder cancer (precautionary)
Side Effects:
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Common: Gastric discomfort, flatulence, mild elevation in liver enzymes
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Rare: Myopathy (especially with statin use), edema
Pregnancy & Lactation:
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Not recommended during pregnancy unless clearly necessary
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Avoid use during lactation unless benefits outweigh risks
Precautions & Warnings:
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Monitor liver function periodically
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Use cautiously in patients with a history of edema or heart failure
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Regular lipid profile testing is recommended
Overdose Effects:
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No major toxicity reported with overdose
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Symptomatic and supportive treatment is recommended
Therapeutic Class:
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Dual PPAR α/γ Agonist / Anti-Diabetic & Lipid-Lowering Agent
Storage Conditions:
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Store below 30°C in a dry place
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Protect from direct sunlight and moisture
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Keep out of reach of children
Product Category:
Metabolic Disorders / Diabetic Dyslipidemia / Lipid-Lowering Agents
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